Metastatic Head and Neck Squamous Cell Carcinoma; Recurrent Head and Neck Squamous Cell Carcinoma
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Estimated readout windows: registry primary-completion date + 6-12 weeks. Windows already open are shown from "Now". Drug names link to ClinicalTrials.gov.
Partnerships MSD (clinical trial collaboration and supply; MSD provides pembrolizumab)
Indications
first-line recurrent/metastatic HPV-negative head and neck squamous cell carcinoma (with pembrolizumab)(Phase 2/3)
Catalysts
— end of 2026
— mid-2027
Status note FORTIFI-HN01 Phase 2/3 pivotal trial ongoing; FORTIFI-FLEX alternate-dose study initiated August 2026; no discontinuation disclosed.
Per-asset detail extracted from the 10-Q filed 2026-08-11. Fields the filing does not state are marked "not disclosed" rather than filled from other sources.
Head and Neck Squamous Cell Carcinoma; HPV-Negative Squamous Cell Carcinoma
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Sponsor-matched active trials from ClinicalTrials.gov (3 as sponsor, 3 as collaborator); "Sponsor" = company is the lead sponsor, "Collaborator" = company is a collaborator. The BP column flags big-pharma involvement as lead sponsor or collaborator (excluding the company itself). The Mgmt guide column shows what management guided for readout timing when a guided program matches the trial (hover for the quote, click for the source). Trial listings are not a company pipeline slide.
Institutional holder positions from 13F filings. Q/Q change is vs the prior quarter's filing; % of portfolio is the fund's own reported portfolio weight.
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